Reporter
Part:BBa_K2150015:Design
Designed by: Jianyi Huang Group: iGEM16_UCAS (2016-10-12)
pTet TetX-GFP(fusion protein)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 642
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 1939
Design Notes
The fusion protein can accurately report the expression level of TetX with fluorescence intensity of GFP. PTet is used to test the expression of tetX at the presence of tetracycline conveniently.
Source
PTet comes from BBa_R0040,RBS from BBa_B0034,D.Ter from BBa_B0015. As for fusion protein tetX-GFP, tetX is the same as (K2150101), the protein linker is provided by our advisor Li Hua, and the GFP is from BBa_E0040. We combine this three parts using overlap extension polymerase chain reaction (OE-PCR).